They are buildings, cities and natural wonders. They house the heights of cultural achievement and offer backdrops for our best ideas. Asked to name the most influential place in history, previous and present TIME 100 honorees reflect on locations that have seen and in some cases helped bring about some of the most transformative moments in human experience.
Giant Sequoia trees in snow and fog in Sequoia National Park, Calif.
The ability of the sequoias to survive and grow for 3,000 years is a testament to nature's ability to conjure up ever more creative and elegant ways to embody resiliency in the face of lifelong adversity.
Volkow is a public-health physician
